Kinetic Modeling of Coagulation and Fibrinolysis
نویسندگان
چکیده
منابع مشابه
Fibrinolysis and the control of blood coagulation.
Fibrin plays an essential role in hemostasis as both the primary product of the coagulation cascade and the ultimate substrate for fibrinolysis. Fibrinolysis efficiency is greatly influenced by clot structure, fibrinogen isoforms and polymorphisms, the rate of thrombin generation, the reactivity of thrombus-associated cells such as platelets, and the overall biochemical environment. Regulation ...
متن کاملPathophysiology of intravascular coagulation and fibrinolysis.
When tissue is damaged one reaction is the initiation of the haemostatic mechanism. This involves initially platelet interaction with the damaged vessel walls, platelet aggregation and release at the sites of damage, and subsequent local fibrin formation due to the activation of the coagulation cascade after the 'release' of various factors from the activated platelets -namely, Ca++ ions and ph...
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ژورنال
عنوان ژورنال: IFAC-PapersOnLine
سال: 2019
ISSN: 2405-8963
DOI: 10.1016/j.ifacol.2019.12.242