Kinetic Modeling of Coagulation and Fibrinolysis

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Fibrinolysis and the control of blood coagulation.

Fibrin plays an essential role in hemostasis as both the primary product of the coagulation cascade and the ultimate substrate for fibrinolysis. Fibrinolysis efficiency is greatly influenced by clot structure, fibrinogen isoforms and polymorphisms, the rate of thrombin generation, the reactivity of thrombus-associated cells such as platelets, and the overall biochemical environment. Regulation ...

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Pathophysiology of intravascular coagulation and fibrinolysis.

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ژورنال

عنوان ژورنال: IFAC-PapersOnLine

سال: 2019

ISSN: 2405-8963

DOI: 10.1016/j.ifacol.2019.12.242